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Titlebook: Drugs and the Elderly; Perspectives in Geri J. Crooks,I. H. Stevenson Book 1979 J. Crooks and I. H. Stevenson 1979 absorption.analgesics.an

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樓主: Retina
31#
發(fā)表于 2025-3-26 23:36:17 | 只看該作者
Praeludium: eine Positionsbestimmung,atisfactory, since the study designs have not allowed adequate kinetic analysis of the results obtained. A further criticism of much of the work is that individual pharmaco-kinetic parameters have been measured in isolation, and complete data on the effect of ageing on all the main pharmacokinetic processes are available for only a few drugs.
32#
發(fā)表于 2025-3-27 02:43:02 | 只看該作者
Drug distribution in the elderly the early 1950s (for review, see Brodie, 1964) and later by Bender (1969). More recently, Klotz (1976) has emphasised that ‘distribution is a physicochemical interaction between a drug and the body’ and that ‘the pattern of this distribution is determined by the properties of the two partners’.
33#
發(fā)表于 2025-3-27 08:04:44 | 只看該作者
34#
發(fā)表于 2025-3-27 12:16:56 | 只看該作者
35#
發(fā)表于 2025-3-27 15:29:04 | 只看該作者
Studies on drug absorption and metabolism in the elderlyatisfactory, since the study designs have not allowed adequate kinetic analysis of the results obtained. A further criticism of much of the work is that individual pharmaco-kinetic parameters have been measured in isolation, and complete data on the effect of ageing on all the main pharmacokinetic processes are available for only a few drugs.
36#
發(fā)表于 2025-3-27 20:24:01 | 只看該作者
https://doi.org/10.37307/b.978-3-503-19584-8 the early 1950s (for review, see Brodie, 1964) and later by Bender (1969). More recently, Klotz (1976) has emphasised that ‘distribution is a physicochemical interaction between a drug and the body’ and that ‘the pattern of this distribution is determined by the properties of the two partners’.
37#
發(fā)表于 2025-3-27 22:19:01 | 只看該作者
https://doi.org/10.1007/978-1-4471-1921-0cases. Treatment with a tricyclic antidepressant drug (e.g. amitriptyline, imipramine, nortriptyline) is the usual therapeutic approach. However, many patients fail to show a satisfactory response and there is a high frequency of adverse effects—postural hypotension, confusional states and cardiotoxicity being of particular concern.
38#
發(fā)表于 2025-3-28 04:59:54 | 只看該作者
39#
發(fā)表于 2025-3-28 08:04:21 | 只看該作者
40#
發(fā)表于 2025-3-28 13:16:58 | 只看該作者
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