Titlebook: Drugs Affecting Lipid Metabolism; Rodolfo Paoletti (Dean),David Kritchevsky (Associa Conference proceedings 1987 Springer-Verlag Berlin He

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DRILL

Keith Kroll,James Bassingthwaighteever, studies of new agents have taught us important lessons regarding normal lipid and lipoprotein metabolism. In this presentation I wish to take up three “case histories” in the latter category: (1) bile acid sequestrants; (2) inhibitors of cholesterol biosynthesis, particularly inhibitors of HMG

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Keith Kroll,James Bassingthwaightely hypertriglyceridemia (HTG) (1). These studies, recently published (2,3), can be summarized as follows: HTG states are associated with excessive lipid transfer reactions (4). The lipids that are transferred are the hydrophobic cholesteryl ester (CE) and triglyceride (TG) molecules. The reaction th

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Keith Kroll,James Bassingthwaightets between lipoprotein particles, and receptor-mediated uptake of lipoprotein particles in various organs. Three lipases, hormone-sensitive lipase (HSL), lipoprotein lipase (LPL), and hepatic lipase (HL) represent important points of regulation in lipoprotein metabolism and are consequently major de

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,Dietary and Pharmacological Control of Cholesterol 7α-Hydroxylase,olesterol 7α-hy-droxylase, which catalyzes the introduction of the hydroxyl group in the 7α-position of the cholesterol molecule, is a mixed-function oxidase, cytochrome P 450-dependent and is located in the smooth endoplasmic reticulum of the liver cell (Myant and Mitropoulos 1977).

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https://doi.org/10.1007/978-3-642-71702-4Lipid; Lipoprotein; development; drug; lipide; metabolism; protein; research