Titlebook: Drug Dosing in Obesity; Volume I: Antimicrob Syed Tabish R. Zaidi,Jason A. Roberts Book 2016 Springer International Publishing Switzerland

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Miscellaneous Agents,patients have been made based on the limited available information. There is an urgent need for robust PK studies of many antibiotics that are commonly used in obese patients to guide dosing recommendations.

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N. Bhandari,V. N. Nijampukar,C. P. Vohras in obesity and dosing recommendations are scarce. The purpose of this chapter is to review and summarise the published data to assist in developing dosing recommendations for the use of cephalosporins in obesity.

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R. B. Austin,C. L. Morgan,M. A. Fordccurate initial dosing regimens can be achieved by using a correction factor for obesity when estimating a volume of distribution (V). While for subsequent doses, therapeutic drug monitoring (TDM) remains an essential tool to guide dosing and to prevent unwanted adverse events such as nephrotoxicity.

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