Titlebook: Drug Development; Molecular Targets fo Timothy S. Gaginella,Antonio Guglietta Book 2000 Springer Science+Business Media New York 2000 cytok

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CCKA Receptors in Gastrointestinal Disorders,994a, 1994b) and on CCK receptors (Dourish and Hill, 1987; Jensen et al., 1990; Woodruff and Hughes, 1991; Silvente-Poirot et al., 1993; Williams and Blevins, 1993; D’ Amato et al., 1994; Rasmussen, 1995; Wang, 1995) are available. Moreover, Adler and Beglinger (1991), provide comprehensive coverage

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and peptic ulcer disease has led to even more effective pharmacotherapeutic regimens. Our intent in Drug Development: Molecular Targets for GI Diseases is to bring together hands-on experts to review promising areas of gastrointestinal pharmacology. The contemporary topics covered, from a mechanistic viewpoi978-1-61737-087-8978-1-59259-202-9

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ointestinal disorders. Important new drugs have emerged through the collaborative and complementary efforts of basic scientists, clinicians, and clinical researchers in academia and the pharmaceutical industry. The challenge has been exciting, with a few surprises along the way. Consider peptic ulce

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The Histamine H3 Receptor,Histamine is widely distributed in the body, although with marked quantitative differences in the various species and tissues, and it produces a variety of biological effects by interacting with specific receptors on the surface of target cells.