Titlebook: Dopaminergic Systems and their Regulation; G. N. Woodruff (Director of Pharmacology),J. A. Po Book 1986 The Contributors 1986 dopamine.reg

帽子

A Quarter Century of Brain Dopamine Researchin the shadow of the two other, at that time more prominent, catecholamines, noradrenaline and adrenaline. Even the name “dopamine” was, at the time of the amine’s discovery in the mammalian brain, still new and little known; it seems to have been proposed in about 1951 by Sir Henry Dale (see footno

Outshine

Dopamine Release and Metabolism in Awake Rats after Systemic Neuroleptics as Studied by Brain Dialys, 1963; Javoy et al., 1970; Andén et al., 1971) and the firing activity of DA-neurons (Bunney et al., 1973). Such effects have been taken as evidence for the existence of feedback or autoregulatory mechanism in the dopaminergic system (Carlsson and Lindquist, 1963; Carlsson, 1975; Bunney and Aghajan

FLIRT

Mechanisms Underlying the Modulation of Dopamine Release through Presynaptic Muscarinic Receptorsand the release of previously taken up .H-DA evoked by electrical stimulation from rabbit caudate slices (Helmreich et al., 1982; Lehmann and Langer, 1982) or by K. -depolarization from rat striatal synaptosomes (Raiteri et al., 1982) can be potentiated by acetylcholine (ACh) through the activation

CORD

Interdict

gene-therapy

異教徒

白楊

Dopaminergic Behavioral Responses and Classes of Binding Sites Distinguished by Discriminant Benzamimacological classes can be distinguished. The D-1 and D-2 receptors were initially defined using more or less discriminant agonists and antagonists on two different DA responses e.g. the stimulation of adenylate cyclase namely in the striatum and the inhibition of prolactin release by mammotrophs of

forager

DARPP-32: A Dopamine-regulated Phosphoprotein in the Basal Gangliaet al., 1979). It is specifically enriched in certain populations of neurons, the most prominent of which are the nigrostriatal, mesocortical, and mesolimbic systems which originate in the mesencephalon and terminate in various forebrain regions, and the tuberoinfundibular system which is located in

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