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Titlebook: Diverse Roles of Integrin Receptors in Articular Cartilage; Mehdi Shakibaei,Constanze Csaki,Ali Mobasheri Book 2008 The Editor(s) (if appl

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發(fā)表于 2025-3-21 17:41:19 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Diverse Roles of Integrin Receptors in Articular Cartilage
編輯Mehdi Shakibaei,Constanze Csaki,Ali Mobasheri
視頻videohttp://file.papertrans.cn/283/282081/282081.mp4
叢書名稱Advances in Anatomy, Embryology and Cell Biology
圖書封面Titlebook: Diverse Roles of Integrin Receptors in Articular Cartilage;  Mehdi Shakibaei,Constanze Csaki,Ali Mobasheri Book 2008 The Editor(s) (if appl
描述.Integrins belong to an evolutionary conserved family of adhesion molecules with important biological functions throughout the animal kingdom. They are heterodimeric glycoproteins involved in cell-cell and cell-matrix adhesion and communication. Physiologically they function as intra- and extracellular signalling molecules in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic spread of tumor cells. Integrin beta 1 (?1-integrin) is a multi-functional member of the integrin superfamily and is an integral protein involved in cell-matrix adhesion, cell signalling, cellular defense, cell adhesion, protein binding, protein heterodimerization and receptor-mediated activity. The ?1-integrin family of cell surface receptors appears to play a major role in mediating cell-extracellular matrix interactions that are important in regulating these fundamental processes. ?1-integrins are important adhesion molecules that are highly expressed in articular chondrocytes where they bind to extracellular matrix molecules including fibronectin, laminin, and fibrillar collagens. In addition to mediating cell adhesion, members of the ?1 subfamily of i
出版日期Book 2008
關(guān)鍵詞ageing cartilage; articular cartilage; cartilage; cells; chondrocyte; chondrogenesis; collagen types I/II;
版次1
doihttps://doi.org/10.1007/978-3-540-78771-6
isbn_softcover978-3-540-78770-9
isbn_ebook978-3-540-78771-6Series ISSN 0301-5556 Series E-ISSN 2192-7065
issn_series 0301-5556
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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Undergraduate Lecture Notes in Physicsissue and the interactions between its unique resident cells, the chondrocytes, and the extracellular matrix (ECM) that makes up the bulk of the tissue (Buckwalter and Mankin 1998). Chondrocytes (Fig. 1 ) are the architects of the ECM (Muir 1995), building the macromolecular framework of the ECM fro
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Diverse Roles of Integrin Receptors in Articular Cartilage978-3-540-78771-6Series ISSN 0301-5556 Series E-ISSN 2192-7065
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978-3-540-78770-9The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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0301-5556 m. They are heterodimeric glycoproteins involved in cell-cell and cell-matrix adhesion and communication. Physiologically they function as intra- and extracellular signalling molecules in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic spread
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