Titlebook: Diseases of the Pituitary; Diagnosis and Treatm Margaret E. Wierman Book 1997 Humana Press Inc. 1997 Gonadotropin.growth.growth hormone.hor

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Platform Development Strategiespin structure encompass the variety of pathophysiologic mechanisms underlying gonadotropin deficiency (Table 1). Despite diverse etiologies, the resulting clinical characteristics are shared among the disorders. It is only through understanding the underlying mechanisms that accurate diagnoses can be made and appropriate treatment administered.

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https://doi.org/10.1007/978-1-4757-6666-0whereas the unique TSH β-subunit confers biological specificity to the hormone. The TSH α and β subunits are glycosylated in specific patterns that determine subunit combination, clearance rates, and bioactivity.

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Gonadotropins,produced within the pituitary gland itself (activin, in-hibin, and follistatin). Integration of these different signals by the gonadotrope results in the coordinate secretion of LH and FSH, ultimately promoting sexual maturation and normal reproductive function. Therefore, gonadotropins play a central role in reproductive biology.

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2523-3785 hypopituitarism, deficiency states, strategies for evaluating patients with hyperprolactinemia, Cushing‘s syndrome, acromegaly, and glycoprotein pituitary tumors.978-1-4612-8438-3978-1-4612-3954-3Series ISSN 2523-3785 Series E-ISSN 2523-3793

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Growth Hormone,tron microscopy examination. Electron microscopy reveals several subsets of somatotrophs. Cells of the predominant subset contain abundant, large (500 nm or greater) secretory granules and a lesser number of small granules (200 nm or less), whereas cells of the minority subset are sparsely granulated ..

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