Titlebook: Diseases of the Human Carotid Body; Donald Heath,Paul Smith Book 1992 Springer-Verlag London Limited 1992 Chemodectoma.Chronic carotid glo

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Peptides,concerned with peptides in the human carotid body, which, however, contains at least six. More than 20 years ago Pearse (1969) predicted that a hypothetical peptide hormone, which he called “glomin”, was likely to be present in the glomic chief cells for structurally these are typical APUD cells, wh

adjacent

Carotid Body Hyperplasia,apter 6). It is associated with a diversity of diseases, including pulmonary emphysema, bronchial asthma and systemic hypertension, but the underlying cause of hyperplasia in all of them is probably hypoxaemia. Hyperplasia may be suspected on naked-eye examination at necropsy but it has to be confir

Uncultured

The Carotid Bodies at High Altitude,ic man has been estimated as 15% (Barer et al. 1986) but this is much increased in response to hypobaric hypoxia. Not only is arterial chemoreceptor activity increased in lowlanders in response to the hypobaric hypoxia of high altitude but it is sustained. Under such circumstances it might be antici

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Ventilation and the Carotid Bodies,ct stages of conduction from the atmosphere to the cells. (a) In ventilation, air flows through the trachea and bronchial tree to the alveolar spaces of the lung. (b) Pulmonary diffusion is the stage by which oxygen in the alveoli comes into contact with the alveolar-capillary walls and passes throu

needle

Almitrine,monly in a state of chronic respiratory failure and acute exacerbations brought about by respiratory infections may further impair their blood gas levels. Centrally acting respiratory stimulants such as doxapram have been used in an attempt to improve blood gases, but with limited clinical success a

ARC

macrophage

The Glomic Vasculature,e posterior aspect of the external carotid artery in 5%, from the anterior aspect of the carotid sinus in 5% and from the ascending pharyngeal artery in 2% (Smith et al. 1982; Khan et al. 1988; see Chapter 2). Exceptionally the glomic arteries may arise from the common carotid artery.

chemoprevention

Normal Ultrastructure, sea level as well as in animals exposed to the natural hypoxia of high altitude or the induced hypoxia of simulated altitude in hypobaric chambers. By contrast, with the exception of the chemodectoma, there is scant information on the ultrastructure of either the normal or abnormal human carotid bo

Goblet-Cells

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Theodore G. Th. Pigeaud Ph.D. Leidensinus, which functions as the major baroreceptor of the body (Figs. 1.1 and 1.2). There are, however, histological data to suggest that the carotid body itself is directly sensitive to the level of intravascular pressure within the glomic arteries. Understanding of the physiology and pathology of th