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Human Blood-Brain-Barrier In Vitro Models: Overview and Applicationsquire breaching of the barrier in order to access the central nervous system. Very often brain disorders have early dysfunction of the BBB implicating an important role in pathogenesis and disease progression. The development of human in vitro models is a major advance to allow experimental studies

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Wirtschaft, Gerechtigkeit und Ethik, etwas ungew?hnlichen Weg, der aber den Vorteil hat, die Darstellung sehr anschaulich zu machen: ich entwickle diese Gedanken aus den antiken Autoren und skizziere, wie sie sp?ter weiter entfaltet wurden.

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ed to the Nazi ide- ology. In all these enslaved nations Resistance movements sprang up and they took various forms, one of the most important of which was the work of the illegal press. In the Netherlands, as elsewhere, under- ground newspapers were of the greatest political importance. At the same time a la978-90-247-1764-4978-94-010-1695-7

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Beschleunigte Ubiquitinierung und Degradation der aktivierten Caspase-3 in neutrophilen Granulozytens (n = 7) and septic patients (n = 5) were preincubated with LPS (1 βg/ml) for five hours. Then the proteasome inhibitor PSI (30 βM) was added and after one hour cells were stimulated with either agonistic anti-CD95 (αCD95) antibody (CH11, 100 ng/mL) or medium for another 16 hours. LPS preincubation