| 書目名稱 | Diabetes, Insulin and Alzheimer‘s Disease | | 編輯 | Suzanne Craft,Yves Christen | | 視頻video | http://file.papertrans.cn/271/270452/270452.mp4 | | 概述 | Includes supplementary material: | | 叢書名稱 | Research and Perspectives in Alzheimer‘s Disease | | 圖書封面 |  | | 描述 | .Neurons share more similarities with insulin-producing pancreatic islet cells than with any other cell type. The root of this similarity may lie in the islet’s evolution from an ancestral insulin-producing neuron. The islet-neuron connection becomes less surprising as we learn more about insulin’s involvement in functions far from its traditional role in mediating glucose uptake in muscle. The importance of insulin in the regulation of corporal aging has been established by the dramatic increases in longevity experienced by animals in which the adipose insulin receptor has been genetically eliminated, or in which the insulin-related daf genes have been mutated. New research suggests that, analogous to its influence on corporal aging, insulin also makes important contributions to brain aging and the expression of late-life neurodegenerative disease. Insulin plays a key role in cognition and other aspects of normal brain function. Insulin resistance induces chronic peripheral insulin elevations and is associated with reduced insulin activity both in periphery and brain. The insulin resistance syndrome underlies conditions such as Type 2 diabetes mellitus and hypertension, which are | | 出版日期 | Book 2010 | | 關鍵詞 | Alzheimer; Alzheimer′s disease; Diabetes; Insulin; aging; brain-insulin connection; growth factor; insulin | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-04300-0 | | isbn_softcover | 978-3-642-26281-4 | | isbn_ebook | 978-3-642-04300-0Series ISSN 0945-6066 Series E-ISSN 2196-310X | | issn_series | 0945-6066 | | copyright | Springer-Verlag Berlin Heidelberg 2010 |
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書目名稱Diabetes, Insulin and Alzheimer‘s Disease影響因子(影響力)
書目名稱Diabetes, Insulin and Alzheimer‘s Disease影響因子(影響力)學科排名
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書目名稱Diabetes, Insulin and Alzheimer‘s Disease網絡公開度學科排名
書目名稱Diabetes, Insulin and Alzheimer‘s Disease被引頻次
書目名稱Diabetes, Insulin and Alzheimer‘s Disease被引頻次學科排名
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書目名稱Diabetes, Insulin and Alzheimer‘s Disease年度引用學科排名
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