Titlebook: Development and Plasticity in Sensory Thalamus and Cortex; Reha Erzurumlu,William Guido,Zoltán Molnár Book 2006 Springer-Verlag US 2006 Co

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Pathways to Barrel Development,elopment of the nervous system. The primary somatosensory cortex (S1) of rodents offers a unique opportunity to identify key molecules that regulate glutamate-dependent cortical development because of its unique cytoarchitectonic structures in layer 4 termed “barrels”. Analysis of knockout mice has

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Patterning of the Somatosensory Maps with NMDA Receptors, While a variety of molecular guidance cues help set up the topographic axonal projections in the brain, activity-dependent interactions between pre- and postsynaptic elements play a key role in neural patterning. Here we review our and other groups’ analyses of the phenotypes of mice with various t

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Presynaptic Mechanisms Controlling Axon Terminal Remodeling in the Thalamocortical and Retinogenicutargeting involves axon terminal and synaptic remodeling, as clearly shown in the mammalian visual system. Retinal ganglion cells (RGCs) axon terminals from each eye segregate into separate territories after selective branching and pruning. In the primary somatosensory cortex (S1), the remodeling of

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Book 2006tude of technical and experimental approaches in understanding the development and plasticity of the mammalian sensory thalamus and neocortex and provide a synthetic theoretical framework for future studies..

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Efficiency Wages and Inequalityat express transcription factor Tbr1, transgene ., and other markers. In contrast, GABAergic interneurons in the subplate do not make subcortical (pioneer) axon projections, but instead migrate tangentially and radially through the subplate layer, express transcription factor Dlx, and are born both

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Relations: Hybrid and Environmentalascend to the cortical surface comprising early born cells before descending to their ultimate target cells equivalent to layer 4. This suggests that the initial thalamocortical trajectory has a limited role in final cortical map formation. The normal periphery related pattern is assumed by the thal

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Stand Density and Initial Spacing,s affected by CITK deletion. CIT-K -/- mice are a useful tool to study the role of this molecule in the cellular development of cerebral cortex in vivo, and the development and plasticity of cortical areas and connections in a microencephalic animal. Moreover, they represent an interesting model of