Titlebook: Dendritic Cells in Fundamental and Clinical Immunology; Volume 3 Paola Ricciardi-Castagnoli Book 1997 The Editor(s) (if applicable) and The

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The Liver Sinusoids as a Specialized Site for Blood-Lymph Translocation of Rat Dendritic Cellsntravenous injection of particulates and that they subsequently translocate from the liver vasculature to the hepatic lymph. The present study was performed to demonstrate the migration pathway of blood DC and the existence of specialized vasculature for DC, the liver sinusoids.

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0065-2598 d in Venice (Lido) Italy, from Oc- tober 5 to 10, 1996. The symposium was attended by more than 500 scientists coming from 24 different countries. Studies on dendritic cells (DC) have been greatly hampered by the difficulties in preparing sufficient cell numbers and in a reasonable pure form. At thi

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Distributed Applications Engineering In addition, the success in generating large numbers of DCs underlies two other topics that will recur throughout the congress: the use of DCs for active immunotherapy of human disease, and the dissection of DC function using cell biological and molecular methods.

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The Three-Tier Application Architecturel.. and Romani et al.. have established procedures that make use of the more abundant monocytic CD34-negative and CD14+precursors in peripheral blood. GM-CSF and IL-4 were the necessary cytokines. Both approaches have since been widely used, even up to the stage of clinical trials.

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The Three-Tier Application Architecturene marrow CD34.-derived dendritic cell growth and differentiation, and the addition of c-.-ligand facilitated more detailed phenotypic and functional characterization of the dendritic cell progeny than had previously been possible (4).

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Book 1997e (Lido) Italy, from Oc- tober 5 to 10, 1996. The symposium was attended by more than 500 scientists coming from 24 different countries. Studies on dendritic cells (DC) have been greatly hampered by the difficulties in preparing sufficient cell numbers and in a reasonable pure form. At this meeting

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Driving Gene Expression Specifically in Dendritic Cellsresent a transgenic mouse system in which we targeted gene expression specifically to DC. Using the mouse CD11c promoter we expressed MHC class II I-E molecules specifically on DC of all tissues, but not on other cell types.

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