Titlebook: Dendritic Cells in Fundamental and Clinical Immunology; Volume 2 Jacques Banchereau,Daniel Schmitt Book 1995 The Editor(s) (if applicable)

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Expression of B7 Costimulator Molecules on Mouse Dendritic Cellslate different T-dependent immune responses. How do dendritic cells develop, and how do they act as such effective APCs? We like to divide their mechanism of action into three areas. 1] At the level of “signal one,” dendritic cells express high levels of MHC class II products, they can retain antige

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Development of Rat DC by in Vitro Culture of Bone Marrow Cellsental role in the primary immune response by stimulating quiescent T cells. In this study we describe an in vitro culture system to raise DC from unfractionated bone marrow (BM) cells of LEWIS rats in the presence of low doses of mouse recombinant GM-CSF, that was successfully used in previous work

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Dendritic Cells Differentiated from Human Monocytes through a Combination of IL-4, GM-CSF and IFN-γ ng a high accessory activity and low phagocytic function. In the present study, we demonstrate that under the effect of a triple combination of IL-4, IFN-γ and GM-CSF human blood monocytes are able to differentiate into the cells expressing an identical phenotype and functional features of blood den

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Functional CD40 Antigen on B Cells, Dendritic Cells and Fibroblastspe switch, selections and differentiation into either antibody secreting plasma cells or memory B cells. These antigendependent events occur in different areas of secondary lymphoid organs, as well as other non-lymphoid organs. It requires the interaction of B cells with antigens and numerous cell t

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Characterization of Human Blood Dendritic Cells: Cytokine Profilesonoclonal antibody (mAb) described by Wiirzner ...,designated X-11, recognizes blood DC by binding to a neoepitope on C9 of the TCC or the membrane attack complex. The deposition of TCC on homologous host cells can lead to lysis and, at sublytic concentrations, to the mediation of many inflammatory

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Identification of a Novel Cell Surface Protein Expressed by Murine Epidermal Langerhans Cells and Sos and macrophages, are hampered by the paucity of monoclonal antibodies that differentiate dendritic cells from other accessory cells. At present, only a few monoclonal antibodies (including 33D1 (1), N418 (2) and NLDC-145 (3)) react with antigens that are characteristically (but not necessarily uni

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