Titlebook: Delta Opioid Receptor Pharmacology and Therapeutic Applications; Emily M. Jutkiewicz Book 2018 Springer International Publishing AG, part

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Genetic Variation and Human Disease,easingly well-defined mechanism by which the variant allele reduces production of the beta-amyloid plaques associated with the disease. Additional studies of . variants are necessary to replicate current findings and to delineate the functional roles of relevant polymorphisms.

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Delta Opioid Receptor and Peptide: A Dynamic Therapy for Stroke and Other Neurological Disorders, to reduce cell death following ischemic events. Current research is working to reveal the complex mechanisms of DADLE’s neuroprotective properties. Ultimately, our knowledge of the DOR receptors and agonists has made the opioid system a promising target for therapeutic intervention in many neurolog

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0171-2004 DOR system in disease states, such as pain, mood, addiction, and Parkinson’s disease. Throughout the book, the DOR system as a target for drug development will be discussed.978-3-030-06980-3978-3-319-95133-1Series ISSN 0171-2004 Series E-ISSN 1865-0325

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https://doi.org/10.1007/978-3-322-84112-4he long-term adaptations induced by chronic drug treatment. A better understanding of the specific signaling cascades that regulate these differential behavioral effects would help to guide rational drug design, ultimately resulting in δOR agonists with fewer adverse effects.