Titlebook: Defense of Mucosal Surfaces: Pathogenesis, Immunity and Vaccines; Jean-Pierre Kraehenbuhl,Marian R. Neutra Book 1999 The Editor(s) (if app

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Book 1999and tolerance; immune effectors at mucosal sites; microbial-host interactions at mucosal sites; mucosal vaccines and adjuvants. This multi-disciplinary effort will be a valuable resource for researchers, clinicians and students who need a clear understanding of concepts and a guide to the wide-ranging literature in this very active research area.

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Antibody-Mediated Protection of Mucosal Surfaces, lactoferrin, peroxidase and defensins) secreted by specialized epithelial cells, such as the Paneth cells in the crypts of the small intestine, gastric acid and intestinal hydrolases (proteases, lipases, nucleases) constitute an efficient defense mechanism.

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Plant Expression Systems for the Production of Vaccines,e of plants. This chapter will review the major advances in plant genetic engineering for the production of products for both active and passive immunisation. It will discuss the advantages and disadvantages of the plant expression systems as well as strategies that have been devised to overcome some of the specific problems.

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Dendritic Cells and Langerhans Cells in the Uptake of Mucosal Antigens, It is, however, now clear that there is not a single DC lineage, but that cells with DC properties may arise from at least three lineages and can exist in different states of maturation and activation. The relationships between these lineages and their functional significance in immune responses are far from clear.

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Host Responses to Respiratory Virus Infection and Immunization,s known about the life cycle and spread of these respiratory viruses in vivo. Infection is transmitted primarily by fomites or large-particle aerosols; therefore the initiation site of natural infection is presumed to be the nasopharynx (NP). It is probable that these viruses predominately infect respiratory epithelial cells.

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