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Development of Blood Cells from Mouse Embryonic Stem Cells in Cultureline named OP9. ES cells could give rise to adult type definitive erythrocytes, myeloid and B lineage cells, when the cells were simply cocultured with the OP9 stromal cells. This stromal cell line does not produce functional macrophage colony-stimulating factor (M-CSF) and presumably the deficiency

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ochemical properties. JPs can adopt different shapes, for example, perfectly spherical with two hemispheres having different surface properties, or more commonly snowman or dumbbell shapes. JPs can be amphiphilic if the surface polarity contrast between the two surface regions (Janus lobes) is suffi

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