Titlebook: DNA-Protein Interactions; Andrew Travers Book 1993 Andrew Travers 1993 DNA.Promoter.RNA.bacteria.cell.protein.protein complexes.proteins.r

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Book 1993ximity. It is in such structures that the enzymatic manipulation of DNA in the essential biological processes as DNA replication, transcription and recombination are effected - the complexes are the mediators of the ‘DNA transactions‘ of Hatch Echols.

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patial proximity. It is in such structures that the enzymatic manipulation of DNA in the essential biological processes as DNA replication, transcription and recombination are effected - the complexes are the mediators of the ‘DNA transactions‘ of Hatch Echols.978-0-412-25990-6978-94-011-1480-6

Seizure

DNA structure,tion invariably requires the interaction of protein molecules with specific sequences or structures in the DNA itself. To understand the physical and chemical basis for these interactions we must first consider the structure of DNA and the ways in which this structure can change.

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DNA-protein interactions: sequence specific recognition,direct contact between the polypeptide chain and the exposed edges of the base pairs, primarily in the major groove of B-DNA. These contacts may involve either hydrogen bonds or van der Waals interactions. Molecules which are tightly and rigidly bound to a protein and are thus integral components of