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Titlebook: DNA Replication and the Cell Cycle; 43. Colloquium der G Ellen Fanning,Rolf Knippers,Ernst-L. Winnacker Conference proceedings 1993 Springe

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M. F. Ahmed Shariff,Ruwan D. Nawarathnability to compare and contrast the mechanisms of DNA synthesis and the functions of the replicative enzymes. In much the same way, studies of the mammalian DNA viruses have contributed to an understanding of the enzymology of cellular DNA replication. The choice model system to date for understandin
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Zeqi Chen,Yuehu Liu,Shaozhuo Zhai,Xinzhao Limation about protein phosphatases is available, a detailed understanding of the role of protein phosphorylation in modulating the function of cellular regulatory proteins has been difficult to achieve. Viral regulatory proteins, such as simian virus 40 (SV40) large tumor antigen (T Ag), represent an
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Guanhong Zhang,Muyi Sun,Xiaoguang Zhoucell division (Pardee 1989). One such process is the activation of protein synthesis which is required not only for the G./G. transition, but also for cells to progress through G. and initiate DNA synthesis (Brooks 1977; Rossow et al. 1979). This event is associated with the phosphorylation of a num
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Zeqi Chen,Yuehu Liu,Shaozhuo Zhai,Xinzhao Litachment of ubiquitin, a small (8.5 kDa) and highly conserved protein, to proteolytic substrates prior to degradation (for reviews see Hershko 1991; Finley and Chau 1991; Jentsch et al. 1991, Jentsch 1992a; Jentsch 1992b). This pathway is highly selective and mediates the elimination of abnormal pro
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