Titlebook: DNA Repair and Mutagenesis in Eukaryotes; W. M. Generoso,M. D. Shelby,F. J. Serres Book 1980 Springer Science+Business Media New York 1980

DIKE

Relationship Between Repair Processes and Mutation Induction in Bacteriaia. These include both constitutive and induced, error-free and error-prone systems. The mutation yield from a treatment with a mutagen can be markedly affected by which of these systems is operating in a given bacterial species or strain. The effect of these systems on mutation induction by ultravi

Pedagogy

高爾夫

DNA Repair Pathwaysion repair are described in terms of mechanisms that yield patch sizes of 0, 1, a few (short patch), and many (long patch) bases. The biological and molecular ways of measuring the effects of replication on a damaged template are presented, as are various models of postreplication repair.

起草

Isolation and Characterization of Repair-Deficient Mutants of ,ing replication, repair and recombination and to define the relationship of each of these functions to mutation production..Nineteen loci which confer enhanced sensitivity to killing by methyl methanesulfonate have been detected on the X and second chromosomes. These loci can be grouped into five se

Bravura

Effects of Recombination-Deficient and Repair-Deficient Loci on Meiotic and Mitotic Chromosome Behavthat there is substantial overlap between the functions used in various aspects of DNA metabolism in Drosophila. Most loci first identified by either recombination-defective or mutagen-sensitive mutants have been shown also to function in nonmutagenized mitotic cells where their action is necessary

前奏曲

Biochemical Characterization of Repair-Deficient Mutants of Drosophila genetic loci in . have been shown to be defective in DNA synthesis or repair. Mutants associated with the following genetic loci exhibit defects in the corresponding metabolic functions:.The pleiotropic effect of several of these mutants indicates that their wild type alleles normally participate i

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