Titlebook: DNA Profiling and DNA Fingerprinting; J?rg T. Epplen,Thomas Lubjuhn Book 1999 Springer Basel AG 1999 Chromosom.DNA.PCR.Single Nucleotide P

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DNA Profiling in Veterinary Medicine,osis of genetic diseases and for the sexing of animals. The recent development of medium-density genetic linkage maps permits even initial mapping projects in domestic animal flocks (for a review see [1]). In horses, as well as other farm animals, selective breeding (e.g. for speed or jumping abilit

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Multilocus DNA Fingerprinting,followed by probing with suitable probes is now an obsolete methodology. This is because such procedures are laborious, require much technical skill, depend on high molecular weight DNA to start with and do not easily lend themselves to automation and electronic data storage. Multilocus DNA fingerpr

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Various Levels of (Epi)Genetic Diversities as Demonstrable via Simple Repeated Sequences, Such conspicuous blocks are known to be widely interspersed throughout eukaryotic genomes and in a number of prokaryotic chromosomes (see the chapter of van Helden, this volume). On the population level, longer simple repeat blocks tend to vary in the numbers of tandem repeat units, generating an e

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Mitochondrial DNA: Diversity Analysis and Possible Pitfalls, relics of an α-proteobacterium that integrated into a thus far poorly understood host cell to constitute a primordial, complex eukaryotic cell ([1] and references therein). The endosymbiosis was followed by a considerable transfer of genetic material from the eubacterium to the host cell, resulting

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PCR-based DNA Profiling of Human Y Chromosomes,ry time spans new mutations are quickly shuffled by recombination, generating genetic uniqueness. The situation of autosomal and X-chromosomal markers contrasts markedly with that of the Y chromosome, which exhibits in most of its length (Y-specific part) a haploid state and lack of recombination. T

induct

PCR-SSCP: A Method for Reliably Detecting Single Nucleotide Polymorphisms in Multifactorial Disease a conserved and functionally relevant nucleotide is affected as in many monofactorial disorders. On the other hand, polymorphisms, which by themselves do not cause a disease, may be relevant in combinations of certain alleles from different genes. The so-called genetic background is responsible for