Titlebook: DNA Fingerprinting: State of the Science; S. D. J. Pena,R. Chakraborty,Alec J. Jeffreys Book 1993 Springer Basel AG 1993 databases.evoluti

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Brief introduction to human DNA fingerprintingo the first instance of the release of a prime suspect proved innocent by DNA evidence (Gill and Werrett, 1987; Wong et al., 1987; see Wambaugh, 1989). By 1987, DNA typing results had been admitted in evidence in criminal courts in the UK and USA, and in 1988 the UK Home Office and Foreign and Commo

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缺乏

Detection, cloning, and distribution of minisatellites in some mammalian genomesns four different minisatellite structures representing 20 kilo bases of the cosmid. These structures are unrelated to each other or to the mini satellite family described by Jeffreys et al. (1985). They display different degrees of polymorphism correlated with varying amounts of inner homogeneity.

寡頭政治

Human VNTR mutation and sexate of 7.6% in paternal chromosomes is among the highest reported in any VNTR locus. These findings could indicate that while low-mutant VNTRs might reflect meiotic crossover, mutation events in high-mutant loci could more often be caused by other mechanisms during cell division.

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Arbitrary primed PCR fingerprinting of RNA applied to mapping differentially expressed genesally regulated genes no longer rate limiting. Those PCR products representing genes that are regulated can be cloned from the gel and sequenced. Sequences can be compared to the DNA and protein sequence databases to identify homologs, motifs and members of gene families. The clones can be placed on

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Microsatellites and disease: A new paradigme. Several recent reviews and editorials have discussed the unusual features and characteristics of this new type of mutation (Mandel and Heitz, 1992; Caskey et al., 1992; Rousseau et al., 1992a; Richards and Sutherland, 1992; Rousseau et al., 1992b; Harper et al., 1992; Sutherland and Richards, 199

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Extricate

Genetic variation among the Mapuche Indians from the Patagonian region of Argentina: Mitochondrial Ds from North, Central, and South American populations separated by thousands of miles, suggesting that the origin of the mtDNA patterns predates the migration to the Americas. The mtDNA sequence similarity between Amerind populations suggests that the migration throughout the Americas occurred rapid

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