Titlebook: Cytotoxic Effector Mechanisms; Eckhard R. Podack Conference proceedings 1989 The Editor(s) (if applicable) and The Author(s), under exclus

消毒

https://doi.org/10.1007/978-3-642-73911-8gene; immune response; lymphocytes; polymer; protein

膽大

978-3-642-73913-2The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE

anticipate

Allodynia

Structure and Function of Perforin,t al. (1980). In these early studies, a mixed population of effector cells was used, leaving open the question as to whether the observed membrane lesions were in fact assembled by cytotoxic lymphocytes. Subsequent studies by Podack and Dennert using clonal populations of cytotoxic effector lymphocy

北京人起源

Structure and Function of C8 in the Membrane Attack Sequence of Complement,omplex C5b-9 (.-. 1986): . Assembly of C5b-9 begins with proteolytic conversion of C5 to C5b by the C5 convertases formed as a consequence of complement activation. Development of a transient binding site for C6 leads to formation of a stable C5b-6 dimer. Subsequent binding of C7 and formation of C5

教唆

GEAR

The Molecular Mechanism of Complement C9 Insertion and Polymerisation in Biological Membranes,ies using aged sheep erythrocytes as a target cell suggested a minor role for C9 in this process (. 1968; . and . 1969), the prevailing view now is that the formation of stable cytolytic complexes in fresh erythrocytes or bacteria absolutely requires the presence of C9. There is still, however, cons

SSRIS

The Isolation and Characterization of Two Cytotoxic T-Lymphocyte-Specific Serine Protease Genes,unological, in which potentially relevant molecules were identified by antibodies that interfered with lysis. Such studies suggested the involvement of a number of cell surface molecules in the process but largely their roles appeared to be at the level of target cell binding (. et al. 1983). Second

倫理學(xué)

A Serine Protease-Encoding Gene That Marks Activated Cytotoxic T Cells In Vivo and In Vitro, graft rejection, and the potential culprits in a number of autoimmune diseases. Unfortunately, there is no marker available that specifically identifies these cells in vivo, making it difficult to prove unequivocally that CTLs are the effector cells in these immune functions. Mature T cells are usu

Cholecystokinin

Structure and Function of the Family of Proteoglycans That Reside in the Secretory Granules of Natuns, it has only recently become apparent that these highly acidic macromolecules reside within intracellular secretory granules rather than on the plasma membrane. Heparin proteoglycans are found in the secretory granules of connective tissue mast cells (CTMC) (. et al. 1956; . et al. 1977 a, b; . e