Titlebook: Cytotoxic Drug Resistance Mechanisms; Robert Brown,Uta B?ger-Brown Book 1999 Humana Press 1999

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Cell Sensitivity Assays, important consideration when making comparisons between cell lines, between cytotoxic agents, or when evaluating combinations of drugs. No one cytotoxicity assay is ideal and it is always advisable to support results with those from alternative assays where possible.

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Duncan McConnell B. S., M. S., Ph.D.nhanced repair of ISC has been suggested to play a role in the acquired resistance of some cancers, e.g., chronic lymphocytic leukaemia to nitrogen mustards (.). In addition, the inherent sensitivity (and curability) of some tumors, e.g., testicular cancer, to DNA damaging agents may result in part