Titlebook: Cytokines and Colony Stimulating Factors; Methods and Protocol Dieter K?rholz,Wieland Kiess Book 2003 Humana Press 2003

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Angiogenic Cytokines gene, VEGF has several isoforms generated by alternative splicing (.,.). Of these, the main isoforms VEGF. and VEGF. are secreted soluble glycoproteins, whereas VEGF. and VEGF.6 remain bound to heparan sulfate proteoglycans at the cell surface (.). The importance of VEGF as a potential target for a

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Gene Therapy with Plasmids Encoding Cytokine- or Cytokine Receptor-IgG Chimeric Proteinsely constant delivery of cytokines or their receptors at therapeutic levels. This can be accomplished with viral gene therapy vectors, as well as plasmid DNA expression vectors (nonviral approach). Our laboratory has been particularly interested in the delivery of vectors encoding cytokines and cyto

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https://doi.org/10.1007/978-3-642-73276-8NA (.,.-.). In the investigation of polymorphisms, particular emphasis is directed not only at the coding region, but also at 5. and 3. regulatory regions of the candidate genes, such as the promoter which plays an important part in controlling gene transcription. The 3.-untranslated region (3.UTR)

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Nature of the Antibody Combining Site gene, VEGF has several isoforms generated by alternative splicing (.,.). Of these, the main isoforms VEGF. and VEGF. are secreted soluble glycoproteins, whereas VEGF. and VEGF.6 remain bound to heparan sulfate proteoglycans at the cell surface (.). The importance of VEGF as a potential target for a

Encephalitis

Acetaldehyde

Recruiting Killer Cells for Cancer Therapy,hown that the delivery of secreted biological compounds such as cytokines or their inhibitors (e.g., their soluble receptors) by gene therapy (.-.) can in a single administration achieve long-term therapeutic effects at doses that are various logs of magnitude lower than those used with protein ther

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