Titlebook: Cytokines and Autoimmune Diseases; Vijay K. Kuchroo,Nora Sarvetnick,Lindsay B. Nichol Book 2002 Springer Science+Business Media New York 2

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International Criminal Justice Seriesenesis, neoplasia, differentiation, and a host of other physiological and pathological processes (., .). Considerable interest has been sparked by the discovery that several chemokine receptors are essential invasion coreceptors for human immunodeficiency virus (HIV)-1 and HIV-2 infection of human cells (., .).

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Yoshiyuki Tomizawa,Ikuo Arai,Shinji Gotohrent inflammation of CNS white matter leading to myelin destruction and progressive neurologic impairment.” The major question that then must be addressed is what causes this specific and recurrent inflammation and how can it be regulated.

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cytokines and chemokines are involved in the pathogenesis of autoimmune diseases. The many chapters offer critical reviews the basic mechanisms controlling cytokine induction and regulation, as well as the resulting production of proinflammatory and anti-inflammatory cytokines, the former of which

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Sarah Pickard (Senior Lecturer)rate of approx 1/2000 (.). It is believed that individuals at risk for the disease are genetically predisposed but that induction of the disease requires an environmental trigger; that is, activation of SLE results from a combination of environmental triggers in the context of a susceptible genetic background.

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Book 2002sclerosis, human type 1 diabetes, rheumatoid arthritis, SLE, and myasthenia gravis. Authoritative and state-of-the-art, Cytokines and Autoimmune Diseasehighlights the enormous therapeutic potential of cytokine modulation in the treatment of autoimmune disease.

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