Titlebook: Computational Methods for 3D Genome Analysis; Ryuichiro Nakato Book 2025 The Editor(s) (if applicable) and The Author(s), under exclusive

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Methods for Genome-Wide Chromatin Interaction Analysisnuclear structure observation techniques, and the development of methods utilizing next-generation sequencers (NGSs) have significantly progressed these discoveries. Methods utilizing NGS enable genome-wide analysis, which is challenging with microscopy, and have elucidated concepts of important chr

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Step-by-Step Protocol to Generate Hi-C Contact Maps Using the rfy_hic2 Pipelineutilized in chromatin research. To effectively leverage 3D genomics data obtained through advanced technologies, it is crucial to understand what processes are undertaken and what aspects require special attention within the bioinformatics pipeline. This protocol aims to demystify the Hi-C data anal

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