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Titlebook: Computational Methods for 3D Genome Analysis; Ryuichiro Nakato Book 2025 The Editor(s) (if applicable) and The Author(s), under exclusive

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發(fā)表于 2025-3-21 17:57:56 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Computational Methods for 3D Genome Analysis
編輯Ryuichiro Nakato
視頻videohttp://file.papertrans.cn/243/242255/242255.mp4
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
叢書名稱Methods in Molecular Biology
圖書封面Titlebook: Computational Methods for 3D Genome Analysis;  Ryuichiro Nakato Book 2025 The Editor(s) (if applicable) and The Author(s), under exclusive
描述.This volume covers the latest methods and analytical approaches used to study the computational analysis of three-dimensional (3D) genome structure. The chapters in this book are organized into six parts. Part One discusses different NGS assays and the regulatory mechanism of 3D genome folding by SMC complexes. Part Two presents analysis workflows for Hi-C and Micro-C in different species, including human, mouse, medaka, yeast, and prokaryotes. Part Three covers methods for chromatin loop detection, sub-compartment detection, and 3D feature visualization. Part Four explores single-cell Hi-C and the cell-to-cell variability of the dynamic 3D structure. Parts Five talks about the analysis of polymer modelling to simulate the dynamic behavior of the 3D genome structure, and Part Six looks at 3D structure analysis using other omics data, including prediction of 3D genome structure from the epigenome, double-strand break-associated structure, and imaging-based 3D analysis using seqFISH. Written in the highly successful .Methods in Molecular Biology. series format, chapters include introductions to their respective topics, lists of the necessary materials and tools, step-by-step, readil
出版日期Book 2025
關(guān)鍵詞BEHST; Micro-C data preprocessing; Hi-C; ChIA-PET; STITCHIT
版次1
doihttps://doi.org/10.1007/978-1-0716-4136-1
isbn_softcover978-1-0716-4138-5
isbn_ebook978-1-0716-4136-1Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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CWL-Based Analysis Pipeline for Hi-C Data: From FASTQ Files to Matricestation of the common workflow language (CWL)-based Hi-C analysis pipeline adopted by the 4DN Data Portal ecosystem. This reproducible and portable pipeline generates standard Hi-C contact matrices in formats such as .hic or .mcool from FASTQ files. It enables users to output their own Hi-C data in t
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Systematic Inference of Multi-scale Chromatin Sub-compartments Using Calder2rate chromatin compartment detection, and extended support for input and output formats. Calder2 thus stands as a refined analysis tool, significantly advancing genome-wide studies of 3D chromatin architecture and its functional implications.
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1064-3745 uccessful .Methods in Molecular Biology. series format, chapters include introductions to their respective topics, lists of the necessary materials and tools, step-by-step, readil978-1-0716-4138-5978-1-0716-4136-1Series ISSN 1064-3745 Series E-ISSN 1940-6029
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Internistische extraabdominelle Ursachenformance. This enables users to generate high-resolution datasets with fast turnaround and fewer unmapped reads. Finally, we discuss recent innovations in experimental techniques, bioinformatics techniques, and their applications in clinical testing for diagnostics.
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https://doi.org/10.1007/978-3-658-08361-8This educational chapter aims to guide researchers in using open-source tools for scHi-C analysis, emphasizing critical steps of contact pair extraction, detection of ligation junctions, filtration, and deduplication.
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