Titlebook: Cellular Osmolytes; From Chaperoning Pro Laishram Rajendrakumar Singh,Tanveer Ali Dar,Kriti Book 2024Latest edition The Editor(s) (if appli

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Springer Tracts in Advanced Roboticscts of osmolytes in modulating the protein folding process. Special focus is given towards their effects on protein folding intermediates and on how they regulate the folding pathways. Their ability to induce proper folding of mutant proteins into functionally active conformations is also discussed.

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Involvement of Osmolytes in the Pathophysiology of Various Human Diseases,ders, in the pathophysiology of several important protein misfolding diseases along with their potential as disease markers. Moreover, future insights about their importance as therapeutic targets is also highlighted.

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https://doi.org/10.1007/978-3-319-41947-3 (TMAO), has been extensively studied for its potential to suppress protein aggregation. Recently, TMAO has been appreciated as an excellent chemical chaperone based on its effect to modulate protein folding, aggregation, and its ability to regulate protein quality control in the ER. In the light of

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Louis E. Freund,Wojciech Cellarylasses of osmolytes in modulating protein aggregation, including free amino acids, sugars, polyhydric alcohols, derivatives, urea, and methylamine compounds. Osmolytes can prevent protein aggregation, interact rapidly with surrounding water molecules, and hinder protein misfolding by providing stabi

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Jens Neuhüttler,Inka C. Woyke,Walter Ganzons in the nature of the metabolites present in the normal and cancer individuals. Studies also identified the involvement of specific molecules in key biological processes including, cancer development, cell proliferation, metastasis, and apoptosis. In the present chapter, we try to address insight

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Jens Neuhüttler,Inka C. Woyke,Walter Ganzn maintaining cellular homeostasis, regulating water movement, and protecting proteins from misfolding has been implicated in addressing neurological disorders such as Huntington’s disease, Alzheimer’s disease, and other neurodegenerative as well as genetic disorders. Osmolytes contribute to the pre