Titlebook: Cutaneous Melanoma; Charles M. Balch,Michael B. Atkins,Arthur J. Sober Reference work 2020Latest edition Springer Nature Switzerland AG 20

Encapsulate

Immunology of Melanomalearned from studies of melanoma are now being extended to other types of cancer. Future research aims to develop new strategies to improve the efficacy of current melanoma immunotherapies, such as combination therapies.

創(chuàng)新

Biomarkers for Melanomaomarkers reviewed here comprise tumor tissue-based biomarkers, tumor environment-based biomarkers, soluble biomarkers of the peripheral blood, as well as treatment-associated biomarkers. These biomarkers might not only be useful for diagnostics, prognostication, and prediction of treatment outcomes

起來了

輕打

decipher

Monotonous

Molecular Pathology and Genomics of Melanomaf treatment responses, e.g., . mutations determine the therapeutic response to BRAF inhibitors; or high mutational burden in melanoma is associated with favorable response to immunotherapy. However, despite considerable enthusiasm about our improved understanding of genetic aberrations in melanocyti

Painstaking

Clinical Epidemiology of Melanomatly, algorithms have been developed that combine information about various phenotypic characteristics to derive an overall summary risk score. Such tools are being tested as decision aids to stratify individuals into potential screening programs according to their future risk of melanoma.

公理

Molecular Epidemiology of Melanomaopment and more accurate prediction of an individual’s melanoma risk. The research presented highlights the exciting developments that have come from combining different types of data, including somatic, germline, clinical, pathologic, phenotypic, and environmental risk factors.

GRAIN

大炮

https://doi.org/10.1007/978-3-319-98092-8(tanning). Alterations in components of these pathways may lead to melanomagenesis. Here we present an overview of the genes and pathways that regulate different aspects of the biology of melanocytes as well as their transformation to melanoma.