| 書(shū)目名稱 | Current Topics in Microbiology and Immunology |
| 編輯 | W. Arber,S. Falkow,P. K. Vogt |
| 視頻video | http://file.papertrans.cn/242/241368/241368.mp4 |
| 叢書(shū)名稱 | Current Topics in Microbiology and Immunology |
| 圖書(shū)封面 |  |
| 描述 | The study of the genetic regulation of immune response to natural multidetermi- nant immunogens was undertaken by the method of bidirectional selective breed- ing of High or Low antibody responder lines of mice. Five Selections are described: Selection I, carried out for agglutinin responsiveness to sheep erythrocytes and pigeon erythrocytes alternated in each generation. Selection II, carried out for agglutinin responsiveness to sheep erythrocytes repeated in each generation. Selection III and Selection IV performed respectively for agglutinin response to flagellar or somatic antigens of Salmonella typhimurium and Salmonella oranienburg alternated in each generation. Selection V, performed for passive agglutinin response to bovine serum albumin and rabbit gamma globulin alternated in each generation. In each Selection the character investigated is polygenic. High and Low responder lines diverge progressively during the selective breeding. The maximal interline separation (selection limit) is reached in the 7th-16th generations. High and Low responder lines at selection limit are considered homozygous for the character submitted to se~ection. Their variance is therefore only due to |
| 出版日期 | Book 1979 |
| 關(guān)鍵詞 | Antigen; biology; environment; immune response; immunology; microbiology |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-67322-1 |
| isbn_softcover | 978-3-642-67324-5 |
| isbn_ebook | 978-3-642-67322-1Series ISSN 0070-217X Series E-ISSN 2196-9965 |
| issn_series | 0070-217X |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |
|Archiver|手機(jī)版|小黑屋|
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