Titlebook: Current Problems in Immunology; Otto Westphal (Direktor),Hans-Erhard Bock (Direkto Book 1969 Springer-Verlag Berlin Heidelberg 1969 Antige

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In vitro Stimulation of Lymphoid Cells by Antilymphocytic GlobulinsThe in vitro irritability of lymphoid cells expressed as their proneness to respond to a great number of foreign macromolecules with blastoid transformation and subsequent mitosis seems to be related to their basic immunologic function: the recognition of antigens or foreigness and the production of specific antibody.

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Histological Changes in NZB/NZW MiceEvidence of the spontaneous development of an autoimmune disease in laboratory animals was first reported in 1959 by Bielschowsky, Helyer and Howie. Mice of the strain NZB/Bl develop an autoimmune haemolytic anaemia. An incomplete antibody against red blood cells, reticulocytosis, splenomegaly and a depression of haematocrit were found.

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https://doi.org/10.1007/978-3-540-72151-2cytes, the other humoral factors. Damage of membranes by sensitized mononuclear cells usually does not require participation of serum factors such as complement; and membrane damage by antibody and complement occurs without participation of cells.

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Planung, Errichtung und Betrieb,rs of complement (C1 to C9). The triggering reaction is identical with the material fixation of Cl to the immune complex ; this leads to the formation of Ag-Ab-C1. By its fixation Cl is converted from its chemically inert form to a highly reactive state (“fixed” or “activated” C1). The reactivity of

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https://doi.org/10.1007/978-3-540-72151-2 under the terms of immunogenicity, antigenicity, allergenicity, and tolerogenicity may appear useful (Table 1). Whereas natural macromolecular antigens are usually able to perform simultaneously all possible functions of an antigen, the chemical manipulations of antigenic determinants and of carrie

LIMN

https://doi.org/10.1007/978-3-540-73248-8aramount role. The study of immunity reactions is not only important in itself but it furthers comprehension of other host-environment interactions including those of toxins, drugs or even live agents such as viruses. In all instances the agent or its products, be they noxious or beneficial, have fi

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