Titlebook: Corneal Angiogenesis; A Comprehensive Crit Gordon K. Klintworth Book 1991 Springer-Verlag New York Inc. 1991 Hornhauterkrankung.ophthalmolo

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Sequence of Events in Corneal Neovascularization,bbit (504,505,728,817,818) but the chain of events that precedes and follows the induction of corneal neovascularization has been studied in relatively few experimental models (18,63,106,108,116,143,194,263–265,416,524,666,694). The endothelial cell-specific tubular organelles (Weibel-Palade bodies)

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Quantitation of Corneal Vascularization,tatistical analysis. Many investigators of corneal neovascularization have only indicated whether a particular injury or intracorneal inoculation did or did not induce angiogenesis. In some studies the incidence of an angiogenic response has been used as an indication of the angiogenicity. Because i

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Use of the Cornea to Assay for Angiogenic Activity,wide variety of systems have been used in assays for angiogenic factors. These include implantations into rabbit ear chambers (138,659,815), hamster cheek pouch chambers (416,674), the chick chorioallantoic membrane (CAM) (23,33,44,223,241,482,642,686,757), the rat kidney capsule (336,623), polyeste

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Suppression and Enhancement of Corneal Angiogenesis,angiogenesis in this tissue. Studies in a variety of experimental models have demonstrated a suppression of corneal neovascularization in leukopenic animals. Corneal angiogenesis induced by chemical cautery is severely suppressed under situations that inhibit the inflammatory response and most notab

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Potential Sources of Angiogenic Factors, of the many potential participants in corneal angiogenesis. In theory the angiogenic factor(s) responsible for corneal vascularization could arise from one or more of the following sources: the denatured tissue, the injurious agent, corneal cells, cells of noncorneal origin, pericorneal vascular ce

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Nature of Angiogenic Factor, substance in high concentration. In 1893, Loeb (477) first postulated that some trophic chemical might be responsible for vascularization in general. In 1907 Goldman (298) provided the first clear suggestion that neoplasms produced an angiogenic agent, when he noted that neovascularization could ea

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