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Titlebook: Contemporary Topics in Molecular Immunology; H. N. Eisen,R. A. Reisfeld Book 1976 Springer Science+Business Media New York 1976 antibody.a

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書目名稱Contemporary Topics in Molecular Immunology
編輯H. N. Eisen,R. A. Reisfeld
視頻videohttp://file.papertrans.cn/237/236739/236739.mp4
圖書封面Titlebook: Contemporary Topics in Molecular Immunology;  H. N. Eisen,R. A. Reisfeld Book 1976 Springer Science+Business Media New York 1976 antibody.a
描述Immunochemistry, recently rechristened molecular immunology, has been pre- occupied throughout its long history with the structure and function of antibodies and the specificity of antibody-antigen reactions. With the recent X-ray diffrac- of several crystallized immunoglobulin (Ig) fragments and a whole tion analyses Ig molecule, the three-dimensional structure of antibodies and their ligand- combining sites has been realized, marking the concluding stages of a phase of immunological research that can be traced back at least 75 years. At the same time chemically minded immunologists have been moving in new directions. A substantial beginning in one direction has been made with the purification of messenger RNAs (mRNAs) for Ig chains. Hybridization of these RNAs (or their DNA copies made with the enzyme reverse transcriptase) to cell DNA is beginning to provide convincing estimates of the number of germ-line Ig genes. And some hybridization studies have already yielded suggestive evidence for translocation of V and C genes from separate to contiguous positions in DNA isolated from cells at different stages of differentiation. Moreover, in vitro trans- lation of Ig mRNAs has reveale
出版日期Book 1976
關(guān)鍵詞antibody; antigen; immunoglobulin; immunology
版次1
doihttps://doi.org/10.1007/978-1-4684-8142-6
isbn_softcover978-1-4684-8144-0
isbn_ebook978-1-4684-8142-6
copyrightSpringer Science+Business Media New York 1976
The information of publication is updating

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Allotypes of Light Chains of Rat Immunoglobulins and Their Application to the Study of Antibody Bio is the mouse, but Ig genetic markers have been reported only for H chains. The genetics of several dozen highly inbred strains of rats have also been well studied, particularly their Ig, since the recent discovery of their Ig-producing myeloma tumors (Bazin ., 1973).
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Aruna V. Krishnan,David Feldman regions of the . complex have been defined and have been mapped linearly in the murine IXth linkage group (chromosome No. 17) in the order Κ--- I---S---D with respect to the centromere (Klein, 1970) of that chromosome.
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Portal Hypertension: Extrahepatic Mechanisms a particular linkage group. The possibility exists, however, that the locus which maps in linkage group XI does not contain structural genes for light-chain V regions, but rather is a regulatory locus which governs the expression of structural genes encoded in this linkage group or elsewhere in the genome.
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