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Titlebook: Conjugation and Deconjugation of Ubiquitin Family Modifiers; Marcus Groettrup Book 2010 Landes Bioscience and Springer Science+Business Me

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發(fā)表于 2025-3-21 18:56:12 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱Conjugation and Deconjugation of Ubiquitin Family Modifiers
編輯Marcus Groettrup
視頻videohttp://file.papertrans.cn/236/235568/235568.mp4
概述Focussed on the modifiers ubiquitin, SUMO1/2/3, NED 8, ISG15 and FAT10.Discusses how conjugation enzymes determine specific linkages and how they are interpreted by ubiquitin binding domains.Cross-tal
叢書(shū)名稱Subcellular Biochemistry
圖書(shū)封面Titlebook: Conjugation and Deconjugation of Ubiquitin Family Modifiers;  Marcus Groettrup Book 2010 Landes Bioscience and Springer Science+Business Me
描述? 1 a a 4 ? 17 10 15 ubiquitin; and of 16 VCP 17 18 20 33 34 34 36 p domain. 41 42 42 43 P U 42 47 binding. C. elegans 16 In 21 22 50 51 52 53 13 and UFD 4 10 of Cdc48. 18 30 of Ufd2. COFACTORS 47 23 13 47 47 47 72 15 15 and of Spt23 p90. Ufd2 and Cdc48. In C. elegans 74 16 75 75 76 76 Ufd2 25 54 54 7 56 p47 7 7 80 30 30 81 82 82 but and CD3 26 DUB COFACTORS 30 UFD3 OTU1 4 Cdc48 30 4 OLE1. 15 27 87 REFERENCES 30 REGULATION OF UBIQUITIN MONOUBIQUITINATION UBIQUITINATION 1 32 7 S) d 33 12 13 14 15 18 19 15 20 21 35 15 15 27 15 31 32 31 33 36 monoubiquitination of pol pol 34 37 34 monoubiquitination. 20 35 trans 3 15 REFERENCES by monoubiquitination. Mol Cell; 2009. UBIQUITIN LIGASE ACTIVITY BY Nedd 1 2 of 41 5 6 8 fold. 9 13 14 edd 43 18 18 K M and k 18 22 23 K M 24 25 K M 26 edd 45 18 27 K M K D 18 25 . 8 10 M 21 28 MECHANISM AND REGULATION OF CRLs 34 41 34 edd 47 48 S. pombe 49 51 p27 and I by SCF and SCF 57 58 59 60 CTD CTD CTD CTD in Cul5 CTD CTD CTD 60 18
出版日期Book 2010
關(guān)鍵詞Conjugation; Deconjugation; Groettrup; Modifiers; Ubiquitin; enzymes; regulation
版次1
doihttps://doi.org/10.1007/978-1-4419-6676-6
isbn_softcover978-1-4939-4110-0
isbn_ebook978-1-4419-6676-6Series ISSN 0306-0225 Series E-ISSN 2542-8810
issn_series 0306-0225
copyrightLandes Bioscience and Springer Science+Business Media, LLC 2010
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Control of Deneddylation by the COP9 Signalosome,es an intrinsic metalloprotease with a Jab1/Pad1/MPN+ (JAMM) motif responsible for deneddylation..In the present chapter we focus on the CSN-mediated deneddylation and its biological significance. We summarize latest developments on the mechanism of the CSN and its association with supercomplexes. I
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,Ubiquitin Conjugation and Deconjugation in NF-κB Signaling,itin deconjugation acts as a negative regulatory feedback mechanism that is critically involved in balancing the strength and the duration of the NF-κB response. Moreover, inactivation of deconjugating enzymes can cause sustained NF-κB activity under pathological conditions like chronic inflammation
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發(fā)表于 2025-3-22 09:33:16 | 只看該作者
,Functions of Linear Ubiquitin Chains in the NF-κB Pathway,y studied. In this chapter, we will discuss the distinct roles of linear and K63-linked ubiquitin chains in TNF-α mediated NF-κB activation and the future directions for linear ubiquitin chain research.
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發(fā)表于 2025-3-22 16:13:36 | 只看該作者
Ubiquitin Family Members in the Regulation of the Tumor Suppressor p53,lved in the regulation of p53 ubiquitination but will focus on the enzymes and components of the respective conjugation systems that have been implicated in p53 modification and how the respective modifications (ubiquitin, SUMO-1, NED 8) may impinge on p53 activity.
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發(fā)表于 2025-3-22 19:52:44 | 只看該作者
Ubiquitylation in the ERAD Pathway,rotein of the endoplasmic reticulum membrane and polyubiquitylation in the cytosol by the ubiquitin-activating, ubiquitin-conjugating and ubiquitin-ligating enzyme machinery..Ubiquitylation is required for different steps of the ER-associated degradation process (ERAD). It facilitates efficient extr
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0306-0225 REGULATION OF CRLs 34 41 34 edd 47 48 S. pombe 49 51 p27 and I by SCF and SCF 57 58 59 60 CTD CTD CTD CTD in Cul5 CTD CTD CTD 60 18978-1-4939-4110-0978-1-4419-6676-6Series ISSN 0306-0225 Series E-ISSN 2542-8810
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發(fā)表于 2025-3-23 07:19:08 | 只看該作者
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