Titlebook: Congenital Bleeding Disorders; Diagnosis and Manage Akbar Dorgalaleh Book 2023Latest edition The Editor(s) (if applicable) and The Author(s

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Congenital Bleeding Disorders: Diagnosis and Managementost CBDs (particularly IPFD) are mild bleeding disorders that seldom require medical intervention. The main therapeutic choice in most CBDs is on-demand therapy, while in others, such as severe cases of hemophilia A and B and FXIII deficiency, primary prophylaxis is the recommended treatment option.

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Congenital Fibrinogen Disorders, Diagnosis, and Managementand the impact on the health-related quality of life. Fibrinogen supplementation is the mainstay of bleeding prevention and treatment. In this chapter, we propose an update on the classification, diagnosis, and management of hereditary fibrinogen disorders in several clinical settings.

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Congenital Prothrombin Deficiency: Diagnosis and Managementaboratory tests should be used for diagnosing FII deficiency. FII deficiency is suspected through prolonged prothrombin time (PT) and activate thromboplastin time (aPTT), which is confirmed by a specific FII assay. As no specific prothrombin concentrate is available, prothrombin complex concentrate

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Congenital Factor V Deficiency, Diagnosis, and Managementrothrombin time (PT) and activated thromboplastin time (aPTT). The diagnosis is confirmed by specific laboratory tests including FV antigen and activity assays. The only available therapeutic choice for patients with FV deficiency is fresh frozen plasma (FFP) in which the recommended dose is depende