Titlebook: Concepts in Bioscience Engineering; Richard Dods Textbook 2019 Springer Nature Switzerland AG 2019 Homology Modeling.Protein Threading.Ab

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書目名稱Concepts in Bioscience Engineering影響因子(影響力)




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The Amino Acid Sequences of Proteins Determine Folding and Non-folding, the folded structure of proteins. The manner in which the protein folds is visualized by an energy landscape called a protein folding funnel. This chapter describes the funnel and how it relates to three-dimensional protein structure. This chapter describes the spin glass theory which also visualiz

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Secondary Structure, β-pleated sheets are discussed in this chapter (Secondary Structure). The Ramachandran plot is described with respect to steric hindrance of amino acid side chains. We learn in this chapter how coarse-grained modeling results in reduced polypeptide sequences. The use of mini proteins to describe pr

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Techniques Used to Study Protein Folding,ar magnetic resonance (NMR), and techniques that use NMR. The manner in which NMR determines distances of atoms is explained. Approaches using NMR and pressure to follow folding will be introduced. The methods of F?rster resonance energy transfer (FRET) and photobleaching used to follow folding and

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Protein Folding Software,equences for which three-dimensional structure has been ascertained are used to align the amino acid sequences in other proteins and determine their three-dimensional structures. The known structures are compiled in protein libraries such as the Proton Data Bank (PDB) and SWISS-PROT database. BLAST

項(xiàng)目

Bioscience Engineering of Cells, Tissues, and Organs,ls, tissues, and organs are developed considering the preservation of three-dimensional protein structure. The artificial synthesis of yeast cells promoted by synthetic chromosomes are presented in this chapter. Synthetic bacteria processing the minimum number of synthetic chromosomes is described.

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Bioscience Engineering of Pharmaceutical Delivery Systems,o have their effect in the body. For many years lyophilization has been used for storage of drugs. With medicinals trending toward proteins (immunoglobulins) increasing interest is occurring of how to maintain protein three-dimensional structure. Hydrogels, nanospheres, liposomes and aminoclays are

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https://doi.org/10.1007/978-3-662-41019-6 of proteins and their structures are described in this chapter. They include The Human Genome Project, The Protein Data Bank, and the Human Proteome Project. The earliest theory for how proteins fold, Anfinsen’s thermodynamic hypothesis, and its dependence on Gibbs free energy are presented.