Titlebook: Concepts in Biochemical Pharmacology; Part 3 James R. Gillette,Jerry R. Mitchell Book 1975 Springer-Verlag Berlin · Heidelberg 1975 absorpt

道學(xué)氣

occult

演講

軍械庫(kù)

Drug Latentiation combine with receptors. Harper (1959, 1962) has used the term “l(fā)atentiation” to describe the alteration of drugs to derivatives from which parent drugs are regenerated by enzymatic attack. The term “drug latentiation” will be used here in a broader sense. It will include conversion of drugs to deri

Ventricle

Biotransformation of Drugs to Pharmacologically Active Metabolitesism is known for very few drugs. Several drugs are transformed into as many as one hundred molecular species (metabolites). Depending on their chemical structures, these metabolites may be rapidly excreted, mostly through the urine and the bile. The effects of metabolites of administered drugs may b

ACTIN

The Enterohepatic Circulationsorbed and then return to the liver via the circulation. Many endogenous and exogenous substances can undergo an EHC. Among the endogenous substances are the bile salts, the biliary lipids and biliary phospholipids; the degree of reabsorbability varies considerably for each of these types of substan

Asseverate

Genetically Determined Variations in Drug Disposition and Response in Manome a fundamental principle of pharmacology and a cornerstone of the new field of pharmacogenetics. Multiple factors have been systematically investigated and identified as contributing to individual variations in drug disposition and response. These conditions include age, sex, time of day or seaso

CLEAR

Aging Effects and Drugs in Man, progress is marked primarily by growth and development, but a sharp distinction between these two processes is not possible. Growth refers mainly to increases in size resulting from cellular multiplication of intracellular substance, while development refers to maturation of structures and functio

FACET

Junction