Titlebook: Computational and Statistical Approaches to Genomics; Wei Zhang,Ilya Shmulevich Book 20021st edition Springer Science+Business Media Dordr

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Computational and Statistical Approaches to Genomics978-0-306-47825-3

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Analyzing Protein Sequences Using Signal Analysis Techniques,such as the Wigner-Ville distribution, when appropriately filtered for interference terms, provide frequency as well as spatial information and lead to the ability to identify biologically active sites of certain proteins. However, as illustrated in the homeodomain example, not all mappings are capa

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Parallel Computation and Visualization Tools for Codetermination Analysis of Multivariate Gene Exprression measurements with cDNA microarrays, and its application to a large set of genes. Using PAGE, it was possible to compute coefficients of determination for all possible three-predictor sets from 587 genes for 58 targets in a reasonable amount of time. Given the limited samplesizes currently be

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Human Glioma Diagnosis from Gene Expression Data,tility of genomics in the areas of molecular classification, identification of novel subgroups(so-called “diseases within disease”), identification of new markers for diagnosis, and identification of novel targets for therapeutic intervention. Genomics data analyses have further demonstrated that an

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Alternative Splicing: Genetic Complexity in Cancer,and ultimately protein diversity is achieved through alternative RNA processing. Several examples of changes in the splicing of a single gene transcript that greatly affect cellular function have now been recognized. However, it is also clear that the regulated alternative splicing of gene families

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