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Titlebook: Computational Peptide Science; Methods and Protocol Thomas Simonson Book 2022 The Editor(s) (if applicable) and The Author(s), under exclus

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發(fā)表于 2025-3-21 18:12:28 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Computational Peptide Science
副標(biāo)題Methods and Protocol
編輯Thomas Simonson
視頻videohttp://file.papertrans.cn/233/232888/232888.mp4
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
叢書名稱Methods in Molecular Biology
圖書封面Titlebook: Computational Peptide Science; Methods and Protocol Thomas Simonson Book 2022 The Editor(s) (if applicable) and The Author(s), under exclus
描述.This volume details current and new computational methodologies to study peptides.? Chapters guide readers through antimicrobial peptides, foldability, amyloid sheet formation, membrane-active peptides, organized peptide assemblies, protein-peptide interfaces, prediction of peptide-MHC complexes, advanced free energy simulations for peptide binding, and methods for high throughput peptide or miniprotein design. Written in the format of the highly successful?.Methods in Molecular Biology?.series, each chapter includes an introduction to the topic, lists necessary materials, software, and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols...?..Authoritative and cutting-edge, .Computational Peptides Science: Methods and Protocols .aims to provide concepts, methods, and guidelines to help both novices and experienced workers benefit from today‘s new opportunities and challenges..
出版日期Book 2022
關(guān)鍵詞biomaterials; enzyme substrates; antimicrobial applications; foldamers; Antibody affinity maturation
版次1
doihttps://doi.org/10.1007/978-1-0716-1855-4
isbn_softcover978-1-0716-1857-8
isbn_ebook978-1-0716-1855-4Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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Excited Nuclear States for He-10 (Helium),d at understanding the early aggregation steps of short linear amyloid peptides, the conformational ensemble of the Aβ40/42 dimers in bulk solution, and the stability of Aβ aggregates in lipid membrane models. Then we focus on our studies on the interactions of amyloid peptides/inhibitors to prevent
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發(fā)表于 2025-3-22 10:41:07 | 只看該作者
Excited Nuclear States for Li-8 (Lithium),er, we describe how to utilize MD simulations to predict and study peptide dynamics and how to validate the simulations by circular dichroism, intrinsic fluorescent probe, membrane leakage assay, electrical impedance, and isothermal titration calorimetry. Experimentally validated MD simulations open
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發(fā)表于 2025-3-22 16:01:33 | 只看該作者
Excited Nuclear States for He-6 (Helium), prior to the matching. This extension allows one to reduce the amount of evaluated putative cyclic peptides and to specifically design only those that compete with the strongest protein–protein binding regions. It is illustrated by an application to an MHC class I protein complex.
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Excited Nuclear States for He-3 (Helium),r Proteus software, as a detailed downloadable tutorial. The unfolded model is combined with a folded model that uses molecular mechanics and a Generalized Born solvent. It was optimized for three PDZ domains and then used to redesign them. The sequences sampled are native-like and similar to a rece
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Machine Learning Prediction of Antimicrobial Peptides,multiple functional roles of AMPs annotated in the APD also enabled multi-label predictions (iAMP-2L, MLAMP, and AMAP), which include antibacterial, antiviral, antifungal, antiparasitic, antibiofilm, anticancer, anti-HIV, antimalarial, insecticidal, antioxidant, chemotactic, spermicidal activities,
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