Titlebook: Computational Modeling of Drugs Against Alzheimer’s Disease; Kunal Roy Book 2023Latest edition The Editor(s) (if applicable) and The Autho

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Recent Advances in Computational Modeling of Multi-targeting Inhibitors as Anti-Alzheimer Agentsl drugs. Recently, this approach has played an increasingly important role in the search for new medications to treat AD. Computational modeling helps conserve experimental resources and dramatically accelerates advances in drug research. In this chapter, various computational modeling methods utili

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Basic Information Science Methods for Insight into Neurodegenerative Pathogenesis may lay foundations of neurodegeneration long before clinical neuropathology manifests..It is challenging to intuit which of the many peripheral ailments may be relevant to downstream neuropathology. This chapter thus offers information-based suggestions for how to pursue novel target perception, o

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Network Pharmacology for Drug Repositioning in Anti-Alzheimer’s Drug Developmentchanging them without compromising the essential molecular details. Network pharmacology guides and assists drug repositioning by identifying new drug targets, disease mechanisms, multi-target drugs, drug combinations, and adverse drug reactions through the analysis and molecular visualization of mu

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Kunal RoyIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts

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https://doi.org/10.1007/978-1-0716-3311-3drug development; acetylcholinesterase; butyrylcholinesterase; NMDA receptor; BACE-1 inhibitors

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978-1-0716-3313-7The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines

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Anton Neschadim,Jeffrey A. Medinpairments found are presumed to be the result of synapse disruption and neurochemical deficits. Several neurochemical abnormalities have been found throughout progressive aging, and these have been connected to cognitive dysfunction seen in the sporadic stage of AD. There are various hypotheses expl