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Titlebook: Computational Methods for Processing and Analysis of Biological Pathways; Anastasios Bezerianos,Andrei Dragomir,Panos Balome Book 2017 The

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書目名稱Computational Methods for Processing and Analysis of Biological Pathways
編輯Anastasios Bezerianos,Andrei Dragomir,Panos Balome
視頻videohttp://file.papertrans.cn/233/232738/232738.mp4
概述Presents a guide to one of the most promising research areas in modern life sciences.Provides a hands-on understanding of concepts and methodologies involved in Pathway Analysis via an interdisciplina
叢書名稱SpringerBriefs in Computer Science
圖書封面Titlebook: Computational Methods for Processing and Analysis of Biological Pathways; Anastasios Bezerianos,Andrei Dragomir,Panos Balome Book 2017 The
描述This work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines common workflows shared by several methods. This is followed by a review of pathway and sub-pathway based approaches for systems pharmacology. The work then presents an overview of pathway analysis methods developed to model the temporal aspects of drug- or disease-induced perturbations and extract relevant dynamic themes. The text concludes by discussing several state-of-the-art methods in pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathways..
出版日期Book 2017
關(guān)鍵詞Bioinformatics; Systems Biology; Network Biology; Pathway Analysis; Graph Theory
版次1
doihttps://doi.org/10.1007/978-3-319-53868-6
isbn_softcover978-3-319-53867-9
isbn_ebook978-3-319-53868-6Series ISSN 2191-5768 Series E-ISSN 2191-5776
issn_series 2191-5768
copyrightThe Author(s) 2017
The information of publication is updating

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SpringerBriefs in Computer Sciencehttp://image.papertrans.cn/c/image/232738.jpg
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Submicroscopic Cytodifferentiationetwork- and pathway-based analysis methods can contribute in systems pharmacology are spotlighted. Current approaches for the characterization of drugs mechanism of action, including the elucidation of mechanisms through which disease phenotypes dysregulate biological processes are first discussed.
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CO Observations of Evolved Giant Starsgenes’ expression across various conditions, has become the primary tool for finding biomarkers, drug targets, and understanding the molecular mechanisms of disease. Within this context, a recent trend is that of developing pathway topology-based methods, which integrate the benefits of gene set-bas
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Submicroscopic Cytodifferentiationis type of analysis are discussed, such as the conversion of pathway databases information into graphs (or networks) in order to allow easier interpretation of information and subsequent computational modeling, the contextualization of the transformed pathway graphs using transcriptional data, the u
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