Titlebook: Computational Intelligence Methods for Bioinformatics and Biostatistics; 13th International M Andrea Bracciali,Giulio Caravagna,Roberto Tag

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Constraining Mechanism Based Simulations to Identify Ensembles of Parametrizations to Characterize olite concentrations and they imply the assumption that a biological process is optimized towards a given function. In this work we define a computational strategy exploiting mechanism based simulations as a framework to determine, through a filtering procedure, ensembles of kinetic constants and st

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Process Algebra with Layers: Multi-scale Integration Modelling Applied to Cancer Therapy, modularisation of scale into integrated layers: Object and Population. An Object can represent a molecule, organelle, cell, tissue, organ or any organism. Populations hold specific types of Object, for example, life stages, cell phases and infectious states. The syntax and semantics of this novel l

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A Problem-Driven Approach for Building a Bioinformatics GraphDB,g amount of data produced is difficult to analyse and interpret in terms of time consuming and number of different resources used. In this context, the challenge would be to have an integrated and multi component database with a user friendly interface able to solve biological problems without a pri

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Effect of UV Radiation on DPPG and DMPC Liposomes in Presence of Catechin Molecules,s way the damage in biomolecules. In this work, the effect of radiation on liposomes of 1,2-dipalmitoyl-sn-glycero-3-[phospho-rac-(1-glycerol)(sodium salt) (DPPG) and of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is analyzed in the absence and presence of epigallocatechin-3-gallate (EGCG) mo

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Inference in a Partial Differential Equations Model of Pulmonary Arterial and Venous Blood Circulatel is a computationally expensive simulator which, given specific parameter values, solves a system of nonlinear partial differential equations and returns predicted pressure and flow values at different locations in the arterial and venous blood vessels. The standard approach in parameter calibrati

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