Titlebook: Computational Intelligence Methods for Bioinformatics and Biostatistics; 8th International Me Elia Biganzoli,Alfredo Vellido,Roberto Taglia

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A Machine Learning Pipeline for Discriminant Pathways Identificationystems biology. In this work we propose a pipeline that couples a machine learning solution for molecular profiling with a recent network comparison method. The pipeline can identify changes occurring between specific sub-modules of networks built in a case-control biomarker study, discriminating ke

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A Bioinformatics Procedure to Identify and Annotate Somatic Mutations in Whole-Exome Sequencing Data problem to store, manage and analyze terabytes of sequencing data often generated from extremely different data-sources. Our project is mainly focused on the sequence analysis of human cancer genomes, in order to identify the genetic lesions underlying the development of tumors. However, the automa

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Integration of Biomolecular Interaction Data in a Genomic and Proteomic Data Warehouse to Support Bitive data management and analysis support. Integration and comprehensive evaluation of available controlled data can highlight information patterns leading to unveil new biomedical knowledge. For this purpose, the University Politecnico di Milano, is developing a software framework to create and mai

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Machine-Learning Methods to Predict Protein Interaction Sites in Folded Proteins Support Vector Machines (HM-SVM) have been shown to be among the best performing methods on this task. Furthermore, it has been noted that the performance of a predictor improves when its input takes advantage of the difference between observed and predicted residue solvent accessibility. In this p