Titlebook: Comparative Genomics; Using Fungi as Model Per Sunnerhagen,Jure Piskur Book 20061st edition Springer-Verlag Berlin Heidelberg 2006 Telomere

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Comparative genomics and gene finding in fungi, to harvest this information source to derive functional predictions and understanding of genome anatomy. Comparative genomics also tells us stories about the evolution of yeasts and filamentous fungi, and the genome rearrangements that marked their history. For example, several genes encoding prote

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Structural features of fungal genomes,es vary in size more than tenfold, from approximately 2.5 Mbp to 38.8 Mbp. We have performed a computational analysis of DNA structural features of all 18 fungal genomes. The sequenced genomes can be visualised with Genome Atlases, which are graphical representations of the chromosomes, showing DNA

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Duplication of genes and genomes in yeasts,cation of the whole genome. This event occurred in the common ancestor of the . and . species, including .. Recent progress in genome sequencing has allowed the molecular sorting-out process after genome duplication to be investigated in detail. The loci where both copies of the gene were retained,

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Telomeres in fungi,material and preventing genome loss during cell division. At the same time, and in stark contrast, they are remarkably dynamic regions: initial analyses of yeast genomes have shown, through comparative genomics, that regions close to telomeres are prone to rearrangements and duplication and thus are

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Lager brewing yeast,industrial yeasts. The pure cultivation of yeast was established in the early 1880’s with immediate practical success for lager brewing yeast. However, almost a century would elapse before its genetics could be approached in detail, despite the development of the genetics of ., starting in the 1930’