Titlebook: Combination Therapies; Biological Response Allan L. Goldstein,Enrico Garaci Book 1992 Plenum Publishing Corporation 1992 AIDS.gene therapy

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Combination Therapy with Thymic Hormones and Cytokines after Chemotherapy in Cancer Treatmentin tumor therapy, the clinical use of these substances has not produced the expected results. Thus an amount of skepticism has arisen about the therapeutical potentiality of the immunostimulating substances and about the importance of the immune system itself towards neoplasia .

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IL-2 Based Combination Therapy of Malignant Disease: Summary of the Phase I Experience at the Clevelinical evidence of therapeutic synergy. In a Phase I trial of the combination of doxorubicin (DOX) and rIL-2, myelosuppression prevented dose escalation beyond the MTD of DOX 40 mg/m. IV bolus day 1 and rIL-2 3.0 MU/m./24 hr IV on days 2–5, 9–12, and 16–19. Significant increases in peripheral blood

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Combination of Fluorouracil and Interferon: Mechanisms of Interaction and Clinical Studiesents. Preclinical models have suggested interactions between particular BRMs and cytotoxic agents ranging from antagonistic to synergistic. These conflicting preclinical results reflect variations in cell lines, assays, concentrations, duration of the regimen, and sequence of exposure.. The bases fo