Titlebook: Colorectal Cancer; From Pathogenesis to Helmut Karl Seitz,Ulrich A. Simanowski,Nicholas A. Book 1989 Springer-Verlag Berlin Heidelberg 1989

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Biomarkers in the Identification of High-Risk Groupse associated with increased susceptibility to gastrointestinal cancer. In the large intestine, and in the esophagus and stomach of human subjects with either genetic predisposition to cancer, or whose susceptibility is believed due mainly to dietary factors, modifications of epithelial cell prolifer

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Aphorism

Cholesterol, Neutral Sterols and Colorectal Cancertive lack of progress indicates a fundamental weakness in the strategies with which we are attacking the disease as diagnosis and treatment are both focused on the established cancer and ignore its primary cause(s).

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The Role of Bile Acids in Colorectal Carcinogenesisritchevsky and Nair 1971). The most abundant bile acids possess a 24-carbon atom cyclopentanophenanthrene structure. Two primary bile acids common in man and animals are chenodeoxycholic acid (Fig. 1, II. and cholic acid (Fig. 1, III). These compounds are secreted by the liver into bile where they a

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Colorectal Bacteria in Colorectal Carcinogenesistudies were hampered by the lack of equipment and techniques for cultivating the oxygen-sensitive components of the flora. Interest waned in the early decades of this century, and only the role of bacteria as intestinal pathogens was considered, the beneficial effects of the gut flora being ignored.

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Ethanol and Colorectal Carcinogenesisverages have been widely used for their pleasant taste and their mood-altering effects. However, during the last few decades alcohol consumption has steadily increased worldwide, and alcoholism has become one of the major health problems. Haevy alcohol ingestion exerts a deleterious effect on almost