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Titlebook: Clostridioides difficile; Infections, Risk Fac Henning Sommermeyer,Jacek Pi?tek Book 2021 The Editor(s) (if applicable) and The Author(s),

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Helmut Remschmidt,Frank M. Theisenxygen in its environment, . forms metabolically inactive spores, which allow the bacterium to survive for a long time. Spore formation (sporulation) is a complex process resulting in the encapsulation of the bacterium, which protects vital components (DNA and proteins) against destruction by hazardo
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A. Schaub,P. Kümmler,L. Gauck,S. Amannon and increased length of staying in a hospital are associated with an increased risk for CDI. Exposure to antibiotics is a dominant risk for the development of CDI. Therapies with certain antibiotics (e.g., clindamycin and fluoroquinolones) have been identified as carrying particular high CDI risk
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https://doi.org/10.1007/978-3-642-79738-5ncomycin remain the cornerstones of CDI treatment. However, the first . strains have emerged which exhibit a reduced susceptibility against these two antibiotics. Fidaxomicin, a recently approved narrow-spectrum macrocyclic antibiotic, is hardly absorbed from the intestine when given orally. Fidaxom
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