Titlebook: Clinical and Laboratory Medicine Textbook; Marcello Ciaccio Textbook 2023 The Editor(s) (if applicable) and The Author(s), under exclusive

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縮短

Elements of Biomedical Laboratory Organization,ined its structure and functioning. The aim of this chapter is to provide the basic elements and legislative references to understand the organizational context of a biomedical laboratory, the role of different structures, and various professional profiles in the different articulations and duties.

抑制

The Role of Statistics in Laboratory Medicine,formances, definition of reference intervals, and design and conduction of experiments. The knowledge and the correct application of statistical methods allow to deal with the variability of laboratory data, to organize and synthesize information in order to make objective clinical decisions.

Antarctic

The Pre-analytical Phase,surements of constituents in biological fluids. Good laboratory information needs a good “analytical” phase of the measurement. However, everything that happens from the moment when a physician expresses a need for information and the moment when the result of the measurements, properly interpreted,

RAGE

The Quality of Laboratory Results: Sources of Variability, Methods of Evaluation, and Estimation of, the main sources of analytical error are described, and measurement error and the concepts of imprecision, trueness, accuracy, and measurement uncertainty are discussed. Intraindividual and interindividual biological variabilities are described, with some hints about reference intervals and the co

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NORM

Protein Diagnostics, in the blood or in the urine. This chapter first examines the clinical relevance of the condition, which ranges from clinically occult forms, represented by monoclonal gammopathy of undetermined significance, to forms in which the clinical condition is determined by effects due to the peculiar char

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Hematological Diagnostics,e, in the oxygen transporter they contain, hemoglobin. Symptoms accompanying anemia are generally dependent on the extent of the reduction of erythrocyte mass, and consequently of hemoglobin, and on the time within which it occurred. Specifically, a slow progression toward anemia is compensated and