Titlebook: Clinical Trials Design in Operative and Non Operative Invasive Procedures; Kamal M.F. Itani,Domenic J. Reda Book 2017 Springer Internation

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https://doi.org/10.1007/978-1-4615-3006-0omparative effectiveness studies is needed to improve health-care quality and to support the efficient use of limited resources. Pragmatic trials are a type of experimental comparative effectiveness research that are designed to determine the effects of an intervention under the usual condition(s) i

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Introduction to Satellite Communications,ving invasive operative and nonoperative procedures. It focuses on the key elements for sample size determination that includes acquiring a reliable estimate of the treatment effect and variability, the type of endpoint to be analyzed, treatment allocation, and expected recruitment and retention rat

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Frequency and Propagation Considerations,scribing them in depth. This chapter discusses the various types of trials defined by regulatory agencies that are required to move a drug, vaccine, biologic or devices that carry significant risk from preclinical testing to marketing approval. This chapter focuses specifically on early phase trials.

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Primary and Secondary Endpoints associated with the primary research question and hypothesis and therefore is the main outcome of the study. For this reason, it needs to be well defined in advance and needs to be easily measurable with tools that are ideally readily available, simple to use, accurate, and validated. The closer an

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