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Titlebook: Clinical Pharmacology: Current Topics and Case Studies; Markus Müller Book 2016Latest edition Springer International Publishing Switzerlan

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41#
發(fā)表于 2025-3-28 16:02:43 | 只看該作者
Margareta Stefanovic,Michael G. Safonovand that “drug therapy varies widely among individuals” [.]. These two statements set the stage for the discipline of clinical pharmacology (CP) which pursues two main goals: (1) an empirical description of conditions under which drug actions vary in humans and (2) to determine and understand the mo
42#
發(fā)表于 2025-3-28 20:33:58 | 只看該作者
Margareta Stefanovic,Michael G. Safonoves, most notably infections, have extremely satisfying therapeutic success rates, and many serious diseases like diabetes mellitus or some forms of cancer have become chronic, stable diseases and do not lead to extreme shortages of life years any longer. Prime examples for success stories in drug de
43#
發(fā)表于 2025-3-29 00:38:09 | 只看該作者
44#
發(fā)表于 2025-3-29 04:27:29 | 只看該作者
45#
發(fā)表于 2025-3-29 09:45:47 | 只看該作者
46#
發(fā)表于 2025-3-29 14:01:19 | 只看該作者
Ken Chan,Clive Fencott,Barry Hebbronessively establish their safety and ultimately their efficacy. Disasters occur only rarely during phase I trials, which have a remarkable safety record. In 2006, a contract research organization was conducting the first human testing of TGN1412 an immunomodulatory anti-CD28 monoclonal antibody. All
47#
發(fā)表于 2025-3-29 19:36:42 | 只看該作者
48#
發(fā)表于 2025-3-29 20:30:31 | 只看該作者
49#
發(fā)表于 2025-3-30 03:06:15 | 只看該作者
50#
發(fā)表于 2025-3-30 07:34:57 | 只看該作者
Legal Aspects of Safety Critical Systemse the number of compounds where the pharmacokinetics observed at a microdose compared to a therapeutic dose has grown steadily. Based upon the most up-to-date review at the time of writing (2013, reference Lappin et al., Expert Opin Drug Metab Toxicol 9(7):817–834, 2013), there are 35 compounds wher
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